vaccine: Statistical Tools for Immune Correlates Analysis of Vaccine Clinical Trial Data

Various semiparametric and nonparametric statistical tools for immune correlates analysis of vaccine clinical trial data. This includes calculation of summary statistics and estimation of risk, vaccine efficacy, controlled effects (controlled risk and controlled vaccine efficacy), and mediation effects (natural direct effect, natural indirect effect, proportion mediated). See Gilbert P, Fong Y, Kenny A, and Carone, M (2022) <doi:10.1093/biostatistics/kxac024> and Fay MP and Follmann DA (2023) <doi:10.48550/arXiv.2208.06465>.

Version: 1.2.1
Depends: R (≥ 2.10)
Imports: dplyr (≥ 1.0.10), fdrtool (≥ 1.2.17), ggplot2 (≥ 3.4.0), ggpubr (≥ 0.5.0), methods (≥ 4.2.2), rlang (≥ 1.0.6), Rsolnp (≥ 1.16), simest (≥ 0.4), splines (≥ 4.2.2), stats (≥ 4.2.2), SuperLearner (≥ 2.0.28), survival (≥ 3.4.0), survML (≥ 0.0.0.9000), truncnorm (≥ 1.0.8), e1071 (≥ 1.7.12), gam (≥ 1.22.3), ranger (≥ 0.16.0), utils (≥ 4.3.2)
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2024-02-16
Author: Avi Kenny [aut, cre, cph]
Maintainer: Avi Kenny <avi.kenny at gmail.com>
BugReports: https://github.com/Avi-Kenny/vaccine/issues
License: GPL (≥ 3)
URL: https://github.com/Avi-Kenny/vaccine
NeedsCompilation: no
Materials: README NEWS
CRAN checks: vaccine results

Documentation:

Reference manual: vaccine.pdf
Vignettes: Basic package workflow

Downloads:

Package source: vaccine_1.2.1.tar.gz
Windows binaries: r-prerel: vaccine_1.2.1.zip, r-release: vaccine_1.2.1.zip, r-oldrel: vaccine_1.1.0.zip
macOS binaries: r-prerel (arm64): vaccine_1.2.1.tgz, r-release (arm64): vaccine_1.1.0.tgz, r-oldrel (arm64): vaccine_1.1.0.tgz, r-prerel (x86_64): vaccine_1.2.1.tgz, r-release (x86_64): vaccine_1.2.1.tgz
Old sources: vaccine archive

Linking:

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